Projects
Looking Deeper with Light
We are improving hyperspectral imaging methods for biological samples to reveal more information about such biomarkers as cellular surface proteins and nucleic acids.
Maximizing imaging information can help to guide medical procedures in real-time
Improving PCR for Virus Testing
We are improving the speed and accuracy while lowering the cost of rapid polymerase chain reaction (PCR) capability for envelope viruses such as COVID-19. We have identified a strategy for performing PCR that may speed thermal cycling while achieving approximately 1,000,000-fold sample partitioning to accelerate sample preparation without micro-patterning or microfluidics.
Faster, Cheaper, and More Accurate Diagnostics
Exosomes: Messages between cells
Natural biological nanoparticles called exosomes are involved in cancer and neurodegenerative and cardiovascular diseases, as well as in normal physiology. We are developing methods for exosome analysis to improve diagnosis and prognosis of cancer and other diseases and may ultimately lead to better outcomes and new treatment methods.
Earlier Detection of Disease Can Bring Better Outcomes
Unlocking the Signals
If one can detect proteins on the surface of naturally circulating nanoparticles such as exosomes that indicate they have come from a tumor cell, one may have a less invasive “liquid biopsy” from a blood or other fluid sample.
